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Active GIP levels by bioassay showed an apparent peak at 15 min during a 75 g OGTT. Blood glucose (A), plasma insulin (B), plasma active (bioassay), and total (ELISA) GIP (C) and GLP-1 (D) levels in samples collected at the indicated times during a 75 g OGTT (n = 10 in each group). For (C) and (D), white circles, total GIP; black circles, active GIP; white squares, total GLP-1; black squares, active GLP-1. Data are presented as mean ± SEM. *p < 0.05, ****p < 0.0001.
