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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Adv Healthc Mater. 2016 Apr 25;5(15):1868–1873. doi: 10.1002/adhm.201600230

Figure 1.

Figure 1

(a) Semi-logarithmic kinetic plot for the ROP of Carb-PTX using TU and DBU as co-catalysts, [mPEG]0: DBU: TU: [Carb-PTX]0 = 1.0: 2.5: 2.5: 20. (b) Semi-logarithmic kinetic plot for the copolymerization of TMC and Carb-PTX using TU and DBU as co-catalysts, [mPEG]0: DBU: TU: TMC0: [Carb-PTX]0 = 1.0: 2.5: 2.5: 50: 5. The insets show representative GPC curves after a reaction time of 0 min (black), 30 min (blue) and 1 h (red). (c) Plot of drug-loading versus molar feed ratio of Carb-PTX/mPEG. (d) The maximal concentration of free PTX and conjugated PTX from mPEG-polyPTX8.3 in aqueous solution. (e) Plot of micelle size versus molar feed ratio of Carb-PTX/mPEG. (f) Representative cryo-TEM image of mPEG-poly(TMC-PTX1.4) (upper left), mPEG-poly(TMC-PTX2.7) (upper right), mPEG-polyPTX5.8 (lower left) and mPEG-polyPTX8.7 (lower right), respectively. Scale bar 200 nm.