Table 3.
Comparison analyses of transplant outcomes
| Transplant Outcomes | Recipients <65 yr | Recipients ≥65 yr | ||||
|---|---|---|---|---|---|---|
| Young Donor (<65 yr) DBD | Young Donor (<65 yr) DCD | Young Donor (<65 yr) DBD | Young Donor (<65 yr) DCD | Elderly Donor (≥65 yr) DBD | Elderly Donor (≥65 yr) DCD | |
| PNFa | 0.68 (0.34 to 1.36) | 1.34 (0.68 to 2.64) | 1 (Ref) | 1.12 (0.44 to 2.84) | 0.76 (0.31 to 1.87) | 1.93 (0.81 to 4.58) |
| Adjusted model | 0.61 (0.30 to 1.23) | 1.28 (0.64 to 2.56) | 1 (Ref) | 0.98 (0.38 to 2.54) | 0.48 (0.18 to 1.28) | 1.18 (0.45 to 3.06) |
| DGFb | 1.16 (0.75 to 1.80) | 6.94 (4.47 to 10.77)c | 1 (Ref) | 10.45 (5.86 to 18.64)c | 1.77 (1.05 to 2.98)c | 13.94 (7.44 to 26.12)c |
| Adjusted model | 1.08 (0.69 to 1.69) | 7.09 (4.50 to 11.17)c | 1 (Ref) | 10.43 (5.75 to 18.91)c | 1.84 (1.04 to 3.26)c | 14.87 (7.47 to 29.61)c |
| Acute rejection within 3 mod | 1.52 (0.89 to 2.57) | 1.94 (1.14 to 3.30)c | 1 (Ref) | 0.86 (0.39 to 1.89) | 1.35 (0.71 to 2.56) | 3.19 (1.64 to 6.21)c |
| Adjusted model | 1.43 (0.84 to 2.44) | 1.79 (1.04 to 3.08)c | 1 (Ref) | 0.80 (0.36 to 1.76) | 1.24 (0.62 to 2.46) | 2.78 (1.35 to 5.73)c |
| 1-Yr graft failuree | 0.65 (0.43 to 1.00) | 0.73 (0.46 to 1.15) | 1 (Ref) | 1.23 (0.70 to 2.16) | 1.18 (0.71 to 1.95) | 1.52 (0.88 to 2.63) |
| Adjusted model | 0.62 (0.40 to 0.95)c | 0.77 (0.50 to 1.19) | 1 (Ref) | 1.14 (0.65 to 2.00) | 0.98 (0.56 to 1.70) | 1.26 (0.69 to 2.31) |
| 1-Yr death-censored graft failuree | 1.08 (0.58 to 2.01) | 1.44 (0.77 to 2.68) | 1 (Ref) | 1.85 (0.86 to 3.98) | 1.33 (0.63 to 2.80) | 1.98 (0.91 to 4.31) |
| Adjusted model | 0.99 (0.53 to 1.86) | 1.40 (0.75 to 2.63) | 1 (Ref) | 1.70 (0.79 to 3.68) | 1.01 (0.46 to 2.24) | 1.48 (0.64 to 3.42) |
| 1-Yr mortalityf | 0.47 (0.32 to 0.67)c | 0.52 (0.37 to 0.74)c | 1 (Ref) | 1.10 (0.70 to 1.74) | 1.34 (0.91 to 1.99) | 1.64 (1.07 to 2.53)c |
| Adjusted model | 0.49 (0.34 to 0.71)c | 0.52 (0.37 to 0.74)c | 1 (Ref) | 1.11 (0.70 to 1.76) | 1.26 (0.82 to 1.96) | 1.77 (1.09 to 2.86)c |
| 5-Yr graft failuree | 0.70 (0.51 to 0.95)c | 0.66 (0.49 to 0.89)c | 1 (Ref) | 1.08 (0.72 to 1.64) | 1.26 (0.88 to 1.82) | 1.84 (1.25 to 2.71)c |
| Adjusted model | 0.65 (0.46 to 0.91)c | 0.72 (0.51 to 1.01) | 1 (Ref) | 1.03 (0.68 to 1.57) | 1.00 (0.67 to 1.49) | 1.49 (0.97 to 2.29) |
| 5-Yr death-censored graft failuree | 1.41 (0.84 to 2.34) | 1.22 (0.73 to 2.04) | 1 (Ref) | 1.52 (0.78 to 2.96) | 1.44 (0.78 to 2.68) | 2.67 (1.20 to 4.30)c |
| Adjusted model | 1.38 (0.82 to 2.32) | 1.14 (0.68 to 1.91) | 1 (Ref) | 1.37 (0.70 to 2.67) | 1.03 (0.54 to 2.00) | 1.57 (0.79 to 3.11) |
| 5-Yr mortalityf | 0.45 (0.32 to 0.65)c | 0.50 (0.35 to 0.71)c | 1 (Ref) | 1.13 (0.72 to 1.78) | 1.48 (1.00 to 2.19)c | 1.80 (1.17 to 2.76)c |
| Adjusted model | 0.48 (0.33 to 0.69)c | 0.49 (0.35 to 0.70)c | 1 (Ref) | 1.15 (0.73 to 1.83) | 1.35 (0.87 to 2.09) | 1.86 (1.15 to 3.02)c |
In adjusted models, the following variables were taken into account: donor sex, recipient sex, donor hypotensive period, donor terminal Modification of Diet in Renal Disease, donor smoking, CIT, HLA-A mismatch, HLA-B mismatch, HLA-Dr mismatch, recipient original disease, and recipient dialysis vintage.
a
Data available for 2850 patients.
b
Data available for 2668 patients.
c
ORs or HRs with P<0.05.
d
Data available for 2667 patients.
e
Data available for 2850 patients.
f
Data available for 2824 patients.
a,b,d
Presented are ORs (95% CI).
e,f
Presented are HRs (95% CI).