Table 1.
Ref. | Origin | Positive THSD7A Ab | Positive THSD7A Staining |
---|---|---|---|
Tomas et al.2 | Europe/Boston | 15 of 483 Prevalent primary MN (3.1%), two of 67 prevalent secondary MN (3.0%) | Five of five THSD7A Ab positive, zero of 50 THSD7A Ab negative |
Iwakura et al.32 | Japan | Five of 55 incident primary MN (9.1%), zero of 37 incident secondary MN (0%) | |
Hoxha et al.12 | Hamburg/Boston | Nine of 345 incident primary MN (2.6%), 29 of 931 prevalent primary MN (3.1%) | 18 of 18 THSD7A Ab positive, one THSD7A Ab negative |
Larsen et al.4 | United States | Nine of 258 incident MNa (3.5%; two of nine dual positive for THSD7A/PLA2R) |
All native kidney biopsies with MN, except membranous lupus nephritis (International Society of Nephrology/Renal Pathological Society class 5).