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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Thromb Haemost. 2016 Nov 28;15(1):155–162. doi: 10.1111/jth.13532

Table 1. Hematologic parameters of Plg-RKT-/- and Plg-RKT+/+ Mice.

Plg-RKT -/- Plg-RKT+/+ Two Way ANOVA

Male Female Male Female Genotype Gender Genotype*Gender

F P F P F P

Platelets/μl 581,987 ± 15,189 (13) 986,545 ± 73,087 (11) 617,603 ± 154,339 (15) 938,938 ± 44,731 (16) 0 9.358 9.358 0.004 0.123 0.727
WBC/μl 2,008 ± 176 (13) 1,345 ± 159 (11) 1,573 ± 111 (15) 1,438 ± 110 (16) 1.532 0.222 8.325 0.006 3.622 0.063
Lym/μl 777 ± 82 (13) 593 ± 61 (11) 693 ± 67 (15) 626 ± 48 (16) 0.151 0.699 3.643 0.062 0.792 0.378
Gra/μl 919 ± 175 (13) 559 ± 86 (11) 611 ± 64 (15) 581 ± 53 (16) 1.959 0.168 3.647 0.062 2.601 0.113
Eos/μl 66 ± 4 (13) 65 ± 6 (11) 69 ± 4 (15) 72 ± 9 (14) 1.116 0.296 0.069 0.793 0.111 0.740
Mono/μl 313 ± 28 (13) 193 ± 23 (11) 253 ± 30 (15) 230 ± 22 (16) 0.172 0.680 6.963 0.011 3.288 0.076
Hemoglobin g/dl 13.9 ± 0.2 (14) 14.0 ± 0.3 (11) 13.8 ± 0.1 (15) 14 ± 0.2 (15) 0.17 0.844 0.168 0.683 0.408 0.666
HCT, % 41 ± 1 (14) 42 ± 1 (11) 41 ± 1 (15) 41 ± 1 (16) 0.082 0.922 0.373 0.543 0.071 0.932
APTT (sec) 31.9 ± 1.1 (7) 33.5 ± 3.4 (4) 29.4 ± 1.8 (7) 35.4 ± 2.2 (5) 0.03 0.863 4.251 0.053 1.38 0.255
PT (sec) 11.3 ± 0.1 (7) 11.6 ± 0.6 (5) 11.3 ± 0.1 (7) 11.6 ± 0.2 (5) 0.002 0.968 0.855 0.366 0.007 0.968
Fibrinogen mg/ml 2.02 ± 0.31 (18) 1.98 ± 0.22 (13) 1.43 ± 0.14 (13) 1.94 ± 0.31 (10) 1.239 0.271 0.702 0.406 0.953 0.334
Plasminogen μg/ml 50.9 ± 5.6 (18) 81.4 ± 3.6 (13) 51.9 ± 0.5 (13) 80.0 ± 12.9 (9) 0.001 0.980 9.453 0.003 0.017 0.897

Data presented are the mean ±S.E.M. with the number of mice analyzed shown in parentheses. Data were analyzed by two way ANOVA. Significant P values are bolded.