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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Clin Exp Allergy. 2017 Jan 11;47(2):224–235. doi: 10.1111/cea.12866

Figure 6.

Figure 6

Genetic ablation of ROCK2 in CD4 cells does not alter allergen-induced inflammation or AHR. (A) BAL lymphocytes, (B) BAL IL-13, (C) pulmonary IL-13+ Th2 cells, (D) BAL eosinophils, (E) airway responsiveness assessed using changes in G, and (F) pulmonary Th17 cells (CD45+CD3+CD4+IL17+ cells). Airway responsiveness assessed using Rn and H is found in Figure E3. Results are mean ± SEM of data from n=5-12 mice per group, *p<0.05 vs PBS challenge and # p<0.05 vs control mice. Control mice in all studies except flow cytometry were a combination of ROCK2flox/flox and CD4-Cre mice. In flow-cytometric analysis control group was composed only by ROCK2flox/flox mice.