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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Thromb Haemost. 2016 Dec 9;15(1):21–27. doi: 10.1111/jth.13562

Table 3.

Odds Ratio of Individual Stroke Symptoms by Biomarkers in the Fourth versus First Quartile

Individual Stroke Symptoms
Biomarker Unilateral numbness (n=77) Unilateral painless weakness (n=66) Painless loss of vision in one or both eyes (n=51)
Cardiac Function
NT-proBNP, pg/mL
    Model 1 1.36 (0.66, 2.82) 1.54 (0.66, 3.57) 1.22 (0.51, 2.91)
    Model 2 1.52 (0.66, 3.48) 0.95 (0.36, 2.50) 1.23 (0.49, 3.09)
Inflammation
Fibrinogen, mg/dL
    Model 1 0.79 (0.43, 1.42) 1.41 (0.72, 2.75) 1.19 (0.57, 2.49)
    Model 2 0.72 (0.37, 1.39) 1.06 (0.51, 2.20) 1.23 (0.53, 2.83)
CRP, mg/L
    Model 1 2.42 (1.18, 4.96) 1.77 (0.82, 3.81) 4.39 (1.88, 10.23)
    Model 2 2.45 (1.09, 5.51) 1.53 (0.66, 3.56) 4.83 (1.91, 12.19)
Coagulation
FXI, %
    Model 1 1.19 (0.62, 2.30) 1.97 (0.88, 4.39) 1.16 (0.54, 2.49)
    Model 2 1.18 (0.56, 2.48) 1.77 (0.76, 4.15) 1.19 (0.47, 3.00)
D-dimer, μg/mL
    Model 1 1.93 (0.98, 3.82) 2.94 (1.31, 6.59) 2.57 (0.96, 6.89)
    Model 2 2.11 (0.99, 4.52) 3.74 (1.48, 9.43) 2.27 (0.82, 6.28)

Model 1 Adjusted for age, race and sex.

Model 2 Adjusted for age, race, sex, history of heart disease, atrial fibrillation, diabetes mellitus, antihypertensive medication use, current smoking, systolic blood pressure, LVH, lipid lowering medication use and regular aspirin use