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. 2017 Jan 11;33(1):31–40. doi: 10.1007/s12288-017-0776-1

Table 1.

Epidemiological parameters used in Markov Model for valuing consequences

Parameters High dose chemotherapy + autologous stem cell transplant Conventional chemotherapya
Base valueb Source Base value Source
Overall survival (median in months)
 ISS Stage I 67 Kumar et al. [18] 58.8 Ludwig et al. [19]
 ISS Stage II 79 42
 ISS Stage III 20 26.4
Progression free survival (median in months)
 ISS Stage I 32 Kumar et al. [18] 24 Primary analysis of PGI Data
 ISS Stage II 75 18
 ISS Stage III 16 12

aConventional chemotherapy refers to Melphalan and Prednisone regimen

bBase value represent epidemiological parameters based on extensive review of literature, used in the model to form part of our base case analysis