Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 31;11:13. doi: 10.3389/fncel.2017.00013

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 So, Huang, Ge, Cai, Zhang, Lu and Mu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Distribution of new neurons in the granule cell layer (GCL) of runners. (A) A sample photomicrograph of Ki67+ cells in the GCL. (B) Both FE and ME groups have a lower percentage of Ki67+ cells located in the innermost GCL than the CT group. One-way ANOVA, F_2,12 = 5.594, P = 0.0192; post hoc test: ME vs. CT: ^∗∗P < 0.01; ME vs. FE: ^∗P > 0.05; FE vs. CT: P > 0.05; n = 5 in each group. (C) Both FE and ME groups have a higher percentage of Ki67+ cells located in the middle GCL than the CT group. One-way ANOVA, F_2,12 = 10.27, P = 0.0025; post hoc test: ME vs. CT: ^∗∗P < 0.01; ME vs. FE: P > 0.05; FE vs. CT: ^∗P < 0.05; n = 5 in each group. (D) Both FE and ME groups have a higher percentage of Ki67+ cells located in the outermost GCL than the CT group. One-way ANOVA, F_2,12 = 10.80, P = 0.0021; post hoc test: ME vs. CT: ^∗P < 0.05; ME vs. FE: P > 0.05; FE vs. CT: ^∗P < 0.05; n = 5 in each group. (E) A sample photomicrograph of BrdU+ cells in the GCL. (F) Both FE and ME groups have a lower percentage of BrdU+ cells located in the innermost GCL than the CT group. One-way ANOVA, F_2,12 = 14.29, P = 0.0007; post hoc test: ME vs. CT: ^∗∗∗P < 0.001; ME vs. FE: P > 0.05; FE vs. CT: ^∗∗P < 0.01; n = 5 in each group. (G) The ME group has a higher percentage of BrdU+ cells located in the middle GCL than the FE and CT groups. One-way ANOVA, F_2,12 = 10.96, P = 0.0020; post hoc test: ME vs. CT: ^∗∗P < 0.01; ME vs. FE: ^∗P < 0.05; FE vs. CT: P > 0.05; n = 5 in each group. (H) Both FE and ME groups have a higher percentage of BrdU+ cells located in the outermost GCL than the CT group. One-way ANOVA, F_2,12 = 16.25, P = 0.0004; post hoc test: ME vs. CT: ^∗∗∗P < 0.001; ME vs. FE: P > 0.05; FE vs. CT: ^∗∗P < 0.01; n = 5 in each group. (I) Both FE and ME groups have a lower percentage of BrdU+NeuN+ cells located in the innermost GCL than the CT group. One-way ANOVA, F_2,12 = 16.25, P = 0.0004; post hoc test: ME vs. CT: ^∗∗∗P < 0.001; ME vs. FE: P > 0.05; FE vs. CT: ^∗∗P < 0.01; n = 5 in each group. (J) ME group has a higher percentage of BrdU+NeuN+ cells located in the middle GCL than the CT group. One-way ANOVA, F_2,12 = 10.96, P = 0.0020; post hoc test: ME vs. CT: ^∗∗P < 0.01; ME vs. FE: ^∗P < 0.05; FE vs. CT: P > 0.05; n = 5 in each group. (K) Both FE and ME groups have a higher percentage of BrdU+NeuN+ cells located in the outermost GCL than the CT group. One-way ANOVA, F_2,12 = 14.29, P = 0.0007; post hoc test: ME vs. CT: ^∗∗P < 0.01; ME vs. FE: P > 0.05; FE vs. CT: ^∗∗P < 0.01; n = 5 in each group.