Table 3.
ROC curve analysis of the data on WFA-sialylated MUC1, CA19-9, and CEA levels in the serum and bile samples
| Serum | Sensitivity | Specificity | AUC | Cut-off value | ||
|---|---|---|---|---|---|---|
| % | % | |||||
| WFA-sialylated MUC1 | µL/mL | |||||
| Control | vs. | BTC/IhCC | 89.8 | 88.6 | 0.963 | 175.4 |
| Benign biliary disease | vs. | BTC/IhCC | 77.6 | 78.0 | 0.873 | 214.2 |
| CA19-9 | U/mL | |||||
| Control | vs. | BTC/IhCC | 78.5 | 86.4 | 0.857 | 16.5 |
| Benign biliary disease | vs. | BTC/IhCC | 71.3 | 71.1 | 0.753 | 27.6 |
| CEA | ng/mL | |||||
| Control | vs. | BTC/IhCC | 76.0 | 72.7 | 0.767 | 1.6 |
| Benign biliary disease | vs. | BTC/IhCC | 46.2 | 55.4 | 0.523 | 2.8 |
| Bile | % | % | ||||
| WFA-sialylated MUC1 | nL/µg protein | |||||
| Benign biliary disease | vs. | BTC/IhCC | 86.3 | 76.5 | 0.896 | 13.5 |
| CA19-9 | U/µg protein | |||||
| Benign biliary disease | vs. | BTC/IhCC | 68.9 | 60.0 | 0.690 | 1651 |
WFA Wisteria floribunda agglutinin, MUC1 mucin core polypeptide 1, CA19-9 carbohydrate antigen 19-9, CEA carcinoembryonic antigen, BTC biliary tract carcinoma, IhCC intrahepatic cholangiocarcinoma