Table 1.

Curcumin protects against the progression of diabetic nephropathy in db/db mice.

	db/m	db/db	db/db + Cur
Body weight, g	20.11 ± 1.38	44.91 ± 5.57#	35.54 ± 3.02∗
Kidney weight, g	0.14 ± 0.02	0.23 ± 0.04#	0.19 ± 0.03∗
Blood glucose, mmol/L	7.86 ± 0.98	27.44 ± 2.97#	26.34 ± 5.74
SCR, μmol/L	38.48 ± 7.39	49.48 ± 5.59#	41.90 ± 4.71∗
BUN, mmol/L	8.89 ± 2.10	9.58 ± 2.13	9.34 ± 2.30
Urinary albumin, μg/24 h	38.08 ± 23.37	603.83 ± 234.22#	243.14 ± 50.27∗

db/m, nondiabetic mice; db/db, diabetic mice (mock-treated); db/db + Cur, db/db mice treated with curcumin at a dose of 200 mg/kg body weight.

^# p < 0.05, compared with the db/m mice (control); ^∗p < 0.05, compared with the mock-treated db/db mice (n = 6 per group).

Values shown are mean ± SD.

SCR, serum creatinine; BUN, blood urea nitrogen.