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. 2017 Jan 31;7:41695. doi: 10.1038/srep41695

Table 3. Multivariate Cox model analyses of prognostic factors of HCC.

Variable Hazard Ratio 95% CI P
Years of diagnosis     P < 0.001
 1988–1994 1 Reference  
 1995–2001 0.974 0.875–1.084  
 2002–2007 0.803 0.725–0.889  
Age     P < 0.001
 <45 1 Reference  
 45–60 1.617 1.441–1.814  
 61–75 2.098 1.869–2.355  
 >75 2.410 2.115–2.747  
Race     P < 0.001
 Caucasian 1 Reference  
 African American 1.189 1.092–1.295  
 Others* 0.866 0.813–0.921  
Pathological grading     P < 0.001
 High/Moderate 1 Reference  
 Poor/undifferentiation 1.396 1.315–1.483  
Stage     P < 0.001
 Localized 1 Reference  
 Regional 1.797 1.694–1.907  
 Distant 2.924 2.692–3.177  
Tumor size (mm)     P < 0.001
 <3 cm 1 Reference  
 3–5 cm 1.736 1.586–1.901  
 >5 cm 2.529 2.322–2.754  
Marital Status     P < 0.001
 Married 1 Reference  
 Never married 1.109 1.025–1.200  
 Divorced/Separated 1.181 1.082–1.288  
 Widowed 1.198 1.093–1.312  

*Including other (American Indian/AK Native, Asian/Pacific Islander) and unknowns.