Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jan 31;7:41764. doi: 10.1038/srep41764

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) The cell nucleus is targeted and irradiated at time 0 with a single α-particle per point on a cross pattern, each point separated by 4 μm. The re-localization of GFP-RNF8 is observed over 30 min following irradiation and selected time points are shown. (b) Kinetics curves of GFP-RNF8 corresponding to each IRIF obtained from experimetal data. Experimental curves (green points) are normalized and fit (black line) with a model for the first-order response. The intensity fluorescence of GFP-RNF8 protein in the damaged areas is higly variable, as described in each inset by the A parameter. The recruitment time (T) varies independently from the intensity fluorescence reached.