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. 2017 Jan 31;7:41701. doi: 10.1038/srep41701

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Copyright © 2017, The Author(s)

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(a) Experimental scheme for assessing new neuroblasts in the adult hippocampus. (b–e) Sample confocal images of immunostaining of DAPI, MCM2 and DCX. Arrows indicate BrdU⁺/DCX⁺ neuroblasts. Scale bar: (b–e), 20 μm. (f) The dentate gyrus of MECP2 TG mice exhibited increased BrdU⁺/DCX⁺ neuroblasts analyzed at 7 days after 4 doses of BrdU injections. (g) MECP2 TG mice had similar DG volume with WT mice. Values are Mean ± S.E.M (n = 4 animals for each genotype; **P < 0.01, ns: non-significant, student’s t-test).