Figure 3. Hazard/subhazard ratio of vitamin D activator use for all-cause, cardiovascular, infection-related, and malignancy-related death.

The primary adjusted model included central venous catheter use, body weight, mean arterial blood pressure, hemoglobin, and serum concentrations of albumin, calcium, phosphorus, and C-reactive protein. The secondary adjusted model included covariates in the primary model plus the use of calcium carbonate, non-calcium containing phosphorus binders (i.e., sevelamer hydrochloride and lanthanum carbonate), and cinacalcet, and history of invasive parathyroid interventions (i.e., parathyroidectomy and percutaneous ethanol injection therapy) as of the end of 2009.