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. 2017 Jan 31;7:41800. doi: 10.1038/srep41800

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Representative histological images of the bone defect slices from 8 groups at week 4 and 8. (B) The newly formed bone in different groups at week 4 and 8 painted with pseudo color (green). (C) The volume of newly formed bone (mm³) during treatment of CSBD using different graft materials at week 4 and 8. Newly formed bone (*), DBB granules (white triangles). Significant difference between autologous bone-group and other groups, ^#p < 0.05; between 4 and 8 weeks of same group, ^@p < 0.05; DBB + BioC.BMP2 and other groups, ^$p < 0.05.