Figure 4. Anatomy- and physiology-centric approach to understand complex and ageing-related retinopathies and (patho)physiological process networks.

(a) Schematic view summarizing the anatomy- and physiology-centric approach to molecular medicine where networks of processes are used to describe the anatomy and physiology, their interdependencies and modulation. (b) Selection of processes describing the tissue physiology in different retinal compartments and how they affect each other (see Supplementary Table S4 for a more complete list). On the left side the normal physiological process networks are shown and on the right side the pathological process networks together with their modulators (see symbols used in (a)).