Table 2.
ICER league table using iterative optimisation routine
| Intervention | Total cost over 20 years (2014 USD) | Life years saved over rolling baseline | Incremental cost over rolling baseline (2014 USD) | ICER (Cost/LYS) | Final rank |
|---|---|---|---|---|---|
| Baseline | 52,533,337,028 | - | - | - | - |
| Condom availability Max | 51,022,627,998 | 3,899,254 | −1,510,709,029 | Cost-saving | 1 |
| MMC Max | 51,014,858,122 | 951,825 | −7,769,876 | Cost-saving | 2 |
| SBCC1 B + 1 | 51,026,339,070 | 320,591 | 11,480,948 | 36 | Superseded |
| ART (current guidelines) Max | 51,243,805,676 | 2,004,044 | 217,466,606 | 109 | 3 |
| PMTCT Max | 51,314,427,752 | 497,889 | 70,622,076 | 142 | 4 |
| Infant testing at 6 weeks B + 3 | 51,343,303,114 | 116,406 | 28,875,362 | 248 | Superseded |
| Infant testing at 6 weeks Max | 51,352,292,109 | 36,216 | 8,988,995 | 248 | 5 |
| Universal ART Max | 52,658,690,554 | 5,241,734 | 1,306,398,445 | 249 | 6 |
| General population HCT B-2 | 52,002,826,154 | −1,313,947 | −655,864,400 | 499 | Superseded |
| General population HCT B-1 | 52,338,752,835 | 738,355 | 335,926,681 | 455 | Superseded |
| SBCC1 B + 2 | 52,406,222,629 | 111,661 | 67,469,794 | 604 | Superseded |
| General population HCT B + 1 | 53,032,457,662 | 1,012,981 | 626,235,033 | 618 | Superseded |
| SBCC1 B + 3 | 53,098,136,663 | 90,853 | 65,679,001 | 723 | Superseded |
| SBCC1 Max | 53,165,119,118 | 89,429 | 66,982,455 | 749 | 7 |
| General population HCT B + 2 | 53,462,915,656 | 349,206 | 297,796,538 | 853 | Superseded |
| General population HCT B + 3 | 53,755,702,602 | 285,671 | 292,786,946 | 1025 | Superseded |
| SBCC2 B + 2 | 53,778,290,385 | 18,820 | 22,587,782 | 1200 | Superseded |
| SBCC2 Max | 53,777,167,130 | 37,516 | −1,123,255 | Cost-saving | 8 |
| General population HCT Max | 54,066,875,384 | 234,391 | 289,708,254 | 1236 | 9 |
| SBCC3 B-3 | 53,986,493,432 | −50,161 | −80,381,952 | 1602 | Superseded |
| SBCC3 Max | 54,236,500,801 | 137,678 | 250,007,369 | 1816 | 10 |
| HCT for sex workers Max | 54,277,669,534 | 15,576 | 41,168,734 | 2643 | 11 |
| Infant testing at birth B + 2 | 54,547,672,527 | 91,981 | 270,002,992 | 2935 | Superseded |
| Infant testing at birth B + 3 | 54,686,528,178 | 47,297 | 138,855,651 | 2936 | Superseded |
| Infant testing at birth Max | 54,817,666,909 | 44,648 | 131,138,732 | 2937 | 12 |
| PrEP for sex workers Max | 55,022,116,749 | 20,554 | 204,449,839 | 9947 | 13 |
| Testing adolescents B + 1 | 55,538,796,938 | 31,920 | 516,680,189 | 16,187 | Superseded |
| Testing adolescents B + 2 | 56,378,936,369 | 48,428 | 840,139,431 | 17,348 | Superseded |
| Testing adolescents B + 3 | 57,309,365,304 | 48,915 | 930,428,935 | 19,021 | Superseded |
| Testing adolescents Max | 57,956,976,545 | 33,142 | 647,611,241 | 19,540 | 14 |
| PrEP for young women Max | 68,668,523,964 | 406,120 | 10,711,547,418 | 26,375 | 15 |
| Early infant male circumcision B + 1 | 68,755,214,097 | 2 | 86,690,134 | 43,345,067 | Superseded |
| Early infant male circumcision Max | 69,024,142,290 | 3 | 268,928,193 | 89,642,731 | 16 |