Table 1.

Liver function tests and QTc interval (pre and during posaconazole treatment)

	Pre-posaconazole treatment	During posaconazole treatment	p-value
Aspartate transaminase (median, range)	210, 64-982 units/L	109, 48-375 units/L	0.005
Alanine transferase (median, range)	223, 69-1060 units/L	121, 78-409 units/L	0.028
Alkaline phosphatase (median, range)	143, 60-323 units/L	286, 180-478 units/L	<0.001
Gamma-glutamyl transpeptidase (median, range)	104, 33-341 units/L	146, 84-421 units/L	0.039
Total bilirubin (mean+/-SD)	22.38+/-10.45 mg/dL	19.57+/-3.42 mg/dL	0.124
Direct bilirubin (median, range)	16.20, 1.50-26.00 mg/dL	13.30, 9.10-16.30 mg/dL	0.217
QTc interval(median, range)	0.435, 0.350-0.490 s	0.450, 0.400-0.490 s	0.060