Table 3.
Changes in the plasma levels of Ach, TNF-α, IL-6 among the control, pacing, and pacing + SSYX groups at baseline and after long-term intermittent atrial pacing for 8 weeks
| Groups | Ach (µg/ml) | TNF-α (pg/ml) | IL-6 (pg/ml) |
|---|---|---|---|
| Control (n = 6) | |||
| Baseline | 64.77 ± 9.84 | 98.49 ± 18.27 | 193.92 ± 20.99 |
| End-point | 65.94 ± 8.24§ | 100.65 ± 17.46‡ | 196.61 ± 34.63§ |
| Pacing (n = 6) | |||
| Baseline | 63.69 ± 10.67 | 97.03 ± 13.76 | 200.23 ± 30.58 |
| End-point | 23.26 ± 4.07† | 301.68 ± 39.38† | 607.39 ± 54.57† |
| Pacing + SSYX (n = 6) | |||
| Baseline | 66.66 ± 10.35 | 96.55 ± 13.76 | 198.56 ± 37.75 |
| End-point | 43.00 ± 5.84*,§ | 219.25 ± 35.77†,‡ | 397.01 ± 47.58*,§ |
*P<0.01 versus baseline; †P<0.001 versus baseline; ‡P<0.01 versus pacing group; §P<0.001 versus pacing group. TNF-α: Tumor necrosis factor-alpha; IL-6: Interleukin-6; Ach: Acetylcholine; SSYX: Shensong Yangxin.