Table 2.
Primary outcome | All (n = 261) (n, %) |
MCI (n = 122) (n, %) | Normal cognition (n = 139) (n, %) | Univariable OR (95% CI) | Multivariable OR (95% CI)a |
---|---|---|---|---|---|
Cessation | 92 (35.2) | 39 (32.0) | 53 (38.1) | 0.76 [.46–1.27] | .79 [.45–1.38] |
Dose Reduction | 28 (10.7) | 16 (13.1) | 12 (8.6) | 1.60 [.72–3.53] | 2.04 [.86–4.83] |
Cessation + Dose Reduction | 120 (45.9) | 55 (45.1) | 65 (46.8) | .94 [.57–1.52] | 1.07 [.62–1.83] |
Process Outcomes | |||||
Improvement in knowledge | 157 (60.2) | 75 (61.5) | 82 (59.0) | 1.11 [.68–1.82] | 1.06 [.62–1.80] |
Change in beliefs | 147 (56.3) | 67 (54.9) | 80 (57.6) | .89 [.54–1.47] | .84 [.48–1.43] |
Improved self-efficacy for tapering | 144 (55.2) | 68 (55.7) | 76 (54.7) | 1.04 [.64–1.70] | .89 [.52–1.54] |
Discussed intervention with a physician | 102 (39.1) | 43 (35.2) | 59 (42.6) | .73 [.44–1.22] | .75 [.43–1.32] |
Discussed intervention with a pharmacist | 55 (21.1) | 26 (21.3) | 29 (20.8) | 1.02 [.57–1.86] | .89 [.46–1.72] |
Experienced withdrawal symptoms during cessation | 31 (11.9) | 12 (9.8) | 19 (13.7) | .69 [.32–1.49] | .60 [.27–1.35] |
aAnalyses adjusted for living arrangement, education, anxiety as an indication for benzodiazepine treatment and baseline self-efficacy