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. 2017 Jan 31;18:22. doi: 10.1186/s12868-017-0341-8

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Expression of glia markers in Line 61 and wild type mice. Immunofluorescent labeling patterns of neuroinflammation markers in 6 and 9-months old mice. Magnified single channel images show human α-Syn immunoreactivity (red channel; note absence of signal in wild type mice), IBA1 (microglia white), GFAP (astrocytes green), and DAPI (blue). The general labeling pattern of the gliosis markers is similar in either genotype. CX cortex, HC hippocampus, sl stratum lucidum, so stratum oriens, sp stratum pyramidale, sr stratum radiatum. Scale bar A, F, K, P 500 µm; grey images: 50 µm