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. 2017 Jan 31;17:80. doi: 10.1186/s12906-017-1606-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effect of QSEtE pretreatment on the development of atopic dermatitis-like skin lesions in NC/Nga mice. a Clinical skin severity score. Clinical skin severity scores of mice were measured on day 0, and every 7 days after, of the experimental period. Clinical scores are expressed as the mean ± standard deviation (n = 6 per group). *P < 0.05 and ***P < 0.001 vs. vehicle group (Mann-Whitney’s U test). b Biostir-AD-induced skin lesions in dorsal skin. Photographs were taken on the last day (day 28) of the experimental period