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. 2017 Jan 31;16:23. doi: 10.1186/s12944-017-0415-8

Table 1.

Prescription EPA Products [34, 35]

Epadel Vascepa
Year approved 1988 2012
Country Japan USA
Generic name Ethyl icosapentate; icosapent Icosapent ethyl
Structure graphic file with name 12944_2017_415_Figa_HTML.gif graphic file with name 12944_2017_415_Figb_HTML.gif
Molecular formula C22H34O2 C22H34O2
Molecular weight 330.50 330.51
Indications Hyperlipidemia; improvement of ulcer, pain and cold feeling associated with arteriosclerosis obliterans Adjunct to diet to reduce TG levels in adults with severe (≥500 mg/dL) hypertriglyceridemia
Formulation 300-mg, 600-mg, or 900-mg capsules 500-mg or 1000-mg capsules
Dosage and administration 1.8 g/daya (twice daily after meals) 4 g/day (twice daily with food)

aRecommended dosage for treatment of hyperlipidemia; dose may be increased to 1 capsule three times per day if TG levels are abnormal. EPA eicosapentaenoic acid, TG, triglyceride