Table I.

The PDB Templates for Constructing the Homology Models (Model 1, Stage 1) and the Corresponding Sequence Similarities

Model 1	FR		L1		L2		L3		H1		H2		H3
AM1	2X7L	0.87	3LMJ	0.54	3L95	0.71	3MLW	0.15	2VXS	0.86	3MLX	0.60	2BDN	0.50
AM2	4H20	0.95	3O2D	1.00	2I9L	1.00	3O2D	0.88	1F11	1.00	4HK0	1.00	1EHL	0.73
AM3	2XTJ	0.99	2A6D	0.91	1RZI	1.00	3CMO	0.63	1OPG	0.86	3GBM	0.83	1A2Y	0.63
AM4	3MXV	0.92	2R0L	1.00	1T4K	0.86	3IY0	1.00	1EGJ	1.00	1UWX	1.00	1FL6	0.63
AM5	3MLW	0.95	2JB6	0.71	1Q1J	1.00	2J6E	0.73	2B1H	1.00	4DGI	1.00	2R0L	0.75
AM6	3HR5	0.96	1VGE	1.00	2ZUQ	0.71	2J4W	0.89	2VXV	0.86	3GIZ	0.67	2AAB	0.50
AM7	1F58	0.97	1I7Z	0.87	4F9L	0.71	2ZCH	0.67	2AJU	1.00	3J1S	0.60	1QFW	0.63
AM8	2I9L	0.92	1AP2	1.00	1XCT	1.00	1MCP	1.00	1P2C	0.86	1P2C	0.83	1A6U	0.64
AM9	3HMW	0.98	3HI5	0.91	2JIX	1.00	1KCV	0.89	1C5C	1.00	3MLT	0.83	4DN3	1.00
AM10	2I9L	0.94	3W11	1.00	1XCT	1.00	1JRH	0.75	3IY3	0.86	1Z3G	0.83	1E6J	0.55
AM11	2OZ4	0.93	4DGI	0.91	4F2M	1.00	3D9A	0.89	4HK3	1.00	4FQH	0.83	2UUD	0.80

The light and heavy chain templates are taken from a common template framework. The CDR loop templates are chosen according to a combination of stem residue geometry, sequence similarity and database loop clustering (see main text). For each column, the template PDB ID and sequence similarity are listed.