Fig. 6.
Bio-distribution of NO2-OA and its metabolites in adipose tissue of NO2-OA-supplemented HFD-fed mice. NO2-OA was delivered subcutaneously to mice on a HFD (8 mg/kg/day) for 6.5 weeks. Levels of NO2-FAs on adipose tissue associated to the different lipid classes were evaluated after acid hydrolysis. The following species were followed: NO2-OA (A); NO2-SA (B); dinor NO2-SA (C); tetranor NO2-SA (D); and hexanor NO2-SA (E). FFA fraction was not subjected to acid hydrolysis. Range (minimum-maximum) and mean of one experiment with n = 9 are shown.