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. Author manuscript; available in PMC: 2017 Jan 31.
Published in final edited form as: Nat Nanotechnol. 2015 Mar 30;10(4):339–344. doi: 10.1038/nnano.2015.32

Table 1.

Imaging resolution capabilities of current micro- and nanomechanical resonators.

Device type Dimensions (L × w × t) Frequency resolution Resolvable feature size
Closed-loop frequency measurements: predicted resolution
Silicon microbeam11 200 × 33 × 7 (μm) AD = 1 × 10−8 370 nm
Silicon nanobeam7 10 × 0.3 × 0.1 (μm) AD = 8 × 10−8 15 nm
Graphene nanoribbon6 1760 × 200 × 0.14 (nm) AD = 1.3 × 10−6 4.2 nm
Single-walled carbon nanotube15 150 × 1.7 × 1.7 (nm) AD = 2 × 10−6 0.3 nm
Passive thermal-noise frequency measurements in current study
Silicon microcantilever 397 × 29 × 2 (μm) SD = 10−4 9 μm

For closed-loop frequency measurements the diameters of the smallest measureable analytes are tabulated for the cases of a hollow silicon microbeam11, silicon nanobeam7, graphene nanoribbon6 and a single-walled carbon nanotube15. Doubly-clamped beam geometries are employed. The actual device dimensions and deduced experimental values for resonator frequency instability are listed. Frequency fluctuations are characterized by the Allan deviation (AD), which was either reported in the reference indicated, or deduced from the reported mass sensitivity. The resolvable feature size is defined as the approximate size (standard deviation) of an analyte for which the measurement signal-to-noise ratio is unity. The resolvable feature size is calculated assuming a hemispherical particle with a mass density of 2 g cm−3 that strongly adsorbs onto these resonators. We use the analyte-induced frequency shifts in the four lowest-frequency mechanical modes, which are assumed to have identical frequency stabilities (consistent with our experimental findings). For passive thermal-noise frequency measurements we use the observed resolvable feature size in current proof-of-concept measurements. The measured standard deviation (SD) in frequency is given. The differences in resolvable feature size for passive measurement of the microcantilever and the closed-loop measurements of the microbeams are due to their disparity in frequency noise.