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. 2016 Oct 13;17(12):1785–1798. doi: 10.15252/embr.201642416

Figure EV3. The behavioral differences between WT and CAMDI‐KO mice at juvenile and adult stages.

Figure EV3

Related to Fig 2.
  1. Travel time on open‐field test at juvenile and adult stages. For juvenile, n = 13 for WT mice and n = 13 for KO mice. For adult, n = 8 for WT mice and n = 7 for KO mice. *P < 0.05; one‐way ANOVA with Bonferroni's post hoc test (juvenile: F(1, 24) = 5.87, adult: F(1, 13) = 2.55). Data are presented as mean ± SEM.
  2. The velocity in the open‐field test at juvenile and adult stages. For juvenile, n = 13 for WT mice and n = 13 for KO mice. For adult, n = 8 for WT mice and n = 7 for KO mice. One‐way ANOVA with Bonferroni's post hoc test (juvenile: F(1, 24) = 1.74, adult: F(1, 13) = 0.17). Data are presented as mean ± SEM.
  3. Time in center (%) on open‐field test at juvenile and adult stages. For juvenile, n = 13 for WT mice and n = 13 for KO mice. For adult, n = 8 for WT mice and n = 7 for KO mice. *P < 0.05; one‐way ANOVA with Bonferroni's post hoc test (juvenile: F(1, 24) = 5.75, adult: F(1, 13) = 0.63). Data are presented as mean ± SEM.
  4. Grooming time in open‐field test at juvenile and adult stages. For juvenile, n = 13 for WT mice and n = 13 for KO mice. For adult, n = 8 for WT mice and n = 7 for KO mice. **P < 0.01; one‐way ANOVA with Bonferroni's post hoc test (juvenile: F(1, 24) = 7.84, adult: F(1, 13) = 0.31). Data are presented as mean ± SEM.
  5. Olfactory function test at adult. n = 13 for WT mice and n = 21 for KO mice. One‐way ANOVA with Bonferroni's post hoc test (F(1, 32) = 0.21). Data are presented as mean ± SEM.
  6. Cage‐top hang test at adult. n = 10 for WT mice and n = 16 for KO mice. One‐way ANOVA with Bonferroni's post hoc test (F(1, 24) = 0.32). Data are presented as mean ± SEM.
  7. Three‐chamber social interaction test at adult. Total time spent in each chamber. n = 19 for WT mice and n = 20 for KO mice. Two‐way ANOVA followed by Scheffe's post hoc test (main effect of genotype F(1, 96) = 0.E+0, main effect of chamber F(2, 96) = 282, interaction F(2, 96) = 3.26). Data are presented as mean ± SEM.