Table 1.
Clinicopathological parameters of unpretreated and chemotherapy pretreated mesothelioma patients.
| Characteristics | Unpretreated (n,%) | Pretreated (n,%) | p-value |
|---|---|---|---|
| Number of samples (N) | |||
| 40 | 14 | ||
| Age (years) | 0.043 | ||
| Median | 69 | 63 | |
| Range | 42–81 | 45–73 | |
| Sex | 0.890 | ||
| Male | 34 (85%) | 11 (79%) | |
| Female | 6 (15%) | 3 (21%) | |
| Histological subtype | 0.151 | ||
| Epitheloid | 26 (65%) | 13 (93%) | |
| Sarcomatoid | 5 (13%) | 0 | |
| Biphasic | 9 (22%) | 1 (7%) | |
| Smoker | 0.502 | ||
| No | 7 (18%) | 4 (29%) | |
| Yes | 24 (60%) | 6 (42%) | |
| No data | 9 (22%) | 4 (29%) | |
| Professional asbestos exposure | 0.464 | ||
| No | 10 (25%) | 1 (7%) | |
| Yes | 23 (57%) | 8 (57%) | |
| No data | 7 (18%) | 5 (36%) | |
| Survival | 0.412 | ||
| Alive | 9 (22%) | 5 (36%) | |
| Dead | 31 (78%) | 9 (64%) | |
| Laterality | 0.812 | ||
| Left | 11 (28%) | 5 (36%) | |
| Right | 29 (72%) | 9 (64%) | |
| Surgery | 0.114 | ||
| No surgery | 33 (82%) | 11 (79%) | |
| Diagnostic VATS | 3 (8%) | 1 (7%) | |
| P-D | 1 (2%) | 2 (14%) | |
| EPP | 3 (8%) | 0 | |
| Stage | 0.814 | ||
| I-II | 13 (33%) | 6 (43%) | |
| III-IV | 22 (55%) | 7 (50%) | |
| No data | 5 (12%) | 1 (7%) | |
| Hemoglobin (g/dL) | 0.272 | ||
| < 14.6 (low) | 5 (12%) | 9 (64%) | |
| ≥14.6 (high) | 35 (88%) | 4 (29%) | |
| No data | 0 | 1 (7%) | |
| White blood cell count (×103cells/µL) | 0.754 | ||
| <15.5 (low) | 37 (93%) | 13 (93%) | |
| ≥15.5 (high) | 3 (7%) | 0 | |
| No data | 0 | 1 (7%) | |
| Platelet count (×103 cells/µL) | 1.000 | ||
| <400 (low) | 26 (65%) | 9 (64%) | |
| ≥ 400 (high) | 14 (35%) | 4 (29%) | |
| No data | 0 | 1 (7%) | |
| Neutrophil/lymphocyte ratio | 0.542 | ||
| <mean★ | 16 (40%) | 6 (43%) | |
| ≥mean★ | 24 (60%) | 6 (43%) | |
| No data | 0 | 2 (14%) | |
★, mean of unpretreated samples = 3.3; mean of pretreated samples = 3.2. EPP, extrapleural pneumonectomy; P-D, pleurectomy-decortication; VATS, video-assisted thoracoscopic surgery.