Figure 1.

The frequency of intratumor NKG2A⁺ NK cells is increased in HCC. (A, B) The percentage of NKG2A-expressing NK cells in healthy livers (N = 17) and IT (N = 28) and PT (N = 25) from HCC patients. The differences in the cumulative data were calculated using a Kruskal–Wallis ANOVA followed by Dunn's multiple comparisons test. (C) NKG2A expression in NK cells from the paired IT and PT from each HCC patient (N = 23, Wilcoxon non-parametric statistical test). (D) The correlation between NKG2A expression in hepatic NK cells from IT and the serum AFP and ALT levels and tumor diameters of HCC patients. Spearman's correlation coefficients are shown.