Figure 3.
Ex vivo biodistribution of [18F]FB-IL-2. Ex vivo biodistribution 50 min after injection of [18F]FB-IL-2 in TC-1 tumor bearing C57B/6 mice, irradiated with a single 14 Gy irradiation or sham-irradiated. One group of irradiated mice was treated with AMD3100, whereas another group of irradiated mice was immunized with single dose of 5 × 106 SFVeE6,7 particles. The ex vivo quantitative estimation of the tracer uptake is expressed as percentage of the injected dose per gram of tissue (%ID/g). Tracer uptake in the tumor of mice subjected to different treatments and in different immunological organs. All the data represent the mean ± standard deviation and the statistical difference are indicated by *p < 0.05, **p < 0.01, and ***p < 0.001.