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. 2017 Jan 31;12(1):e0171140. doi: 10.1371/journal.pone.0171140

Fig 3. Predicted MHC and B-cell epitopes.

Fig 3

Epitopes within the reference sequence of (A) HPV-33 E6 protein; (B) HPV-33 E7 protein; (C) HPV-58 E6 protein; and (D) HPV-58 E7 protein. Red indicates a consensus of the predicted MHC I epitopes binding not less than 10 HLA I alleles. Green indicates a consensus of the predicted MHC II epitopes binding not less than 10 HLA II alleles. Purple indicates a consensus of the predicted B-cell epitopes of which the score ≥ 0.85 for the combined physical-chemical properties. Black arrow indicates corresponding mutation is only a non-synonymous mutation, and blue arrow indicates corresponding mutation is a non-synonymous mutation and positive selection, simultaneously.