Table 4. Site-specific tests for positive selection on HPV-58 E6/E7.

Models	InL	Estimates of parameters	2Δl	E6 Positively selected sites	E7 Positively selected sites
M7	-1273.301	p = 0.005, q = 0.012		NA
M8	-1256.611	p0 = 0.972, p = 35.347, q = 99.000, p1 = 0.028, ω = 24.138	33.38 p<0.01	93K**, 145R**	20T**, 63G**

Tables 3 and 4: ln L, the log-likelihood difference between the two models; 2Δl, twice the log-likelihood difference between the two models; the positively selected sites were identified with posterior probability ≥ 0.9 using Bayes empirical Bayes (BEB) approach, an asterisk indicates posterior probability ≥ 0.95, and two asterisks indicate posterior probability ≥ 0.99. NA means not allowed. NS means the sites under positive selection, but not reaching the significance level of 0.9.