Table 3. ESR1 conversions from primary tumor to metastasis specified by site of metastasis.
| ESR1 conversion primary to metastasis | Metastasis type | N | dCq APOBEC3B | dCq APOBEC3B | P-value* | P-value* |
|---|---|---|---|---|---|---|
| Primary (Average) | Metastasis (Average) | |||||
| Not converted | loco-regional lymph node | 15 | -6.4 | -5.97 | 0.61 | 0.032 |
| distant metastasis | 27 | -5.86 | -4.87 | 0.015 | ||
| ESR1- primary to ESR1+metastasis | loco-regional lymph node | 5 | -8.26 | -6.57 | 0.11 | 0.041 |
| ESR1+ primary to ESR1- metastasis | distant metastasis | 8 | -7.8 | -5.16 | 0.07 |
* Wilcoxon Signed Ranks Test