Table I.
Parameters (n = 43) | SCF group (n = 14) | Control group (NCF, n = 29) | p value |
---|---|---|---|
Age (years ± SD) | 55 ± 12 | 42 ± 11 | 0.001 |
Sex (male), n (%) | 6 (43) | 11 (38) | 0.821 |
Body mass index | 30 ± 4 | 26 ± 4 | 0.002 |
Hypercholesterolemia, n (%) | 7 (50) | 11 (38) | 0.532 |
Family history of CAD, n (%) | 7 (50) | 10 (35) | 0.334 |
Smoking, n (%) | 4 (29) | 8 (28) | 0.902 |
HT, n (%) | 9 (64) | 3 (10) | 0.001 |
Diabetes mellitus, n (%) | 2 (14) | 4 (14) | 0.936 |
Hemoglobin (g/dL) | 13.9 ± 1.2 | 13.5 ± 1.3 | 0.506 |
Total cholesterol (mg/dL) | 195 ± 50 | 188 ± 35 | 0.639 |
LDL (mg/dL) | 129 ± 45 | 119 ± 32 | 0.143 |
HDL (mg/dL) | 40 ± 9 | 45 ± 9 | 0.428 |
Triglycerides (mg/dL) | 144 ± 105 | 141 ± 63 | 0.929 |
Urotensin II (ng/mL) [median ± IQR] | 711.0 [700–721] | 701.5 [666.5–736.5] | 0.006 |
Glucose (mg/dL) [median ± IQR] | 103 [76–130] | 94 [81–107] | 0.050 |
Creatinine (mg/dL) [median ± IQR] | 0.78 [0.67–0.89] | 0.75 [0.6–0.9] | 0.536 |
TIMI frame count measurements | |||
LAD | 31 ± 7 | 61 ± 30 | 0.001 |
LAD (corrected) | 19 ± 4 | 35 ± 18 | 0.001 |
LCx | 23 ± 6 | 32 ± 14 | 0.005 |
RCA | 21 ± 5 | 43 ± 23 | 0.001 |
Mean | 22 ± 4 | 37 ± 14 | 0.001 |
SCF, slow coronary flow; UII, urotensin II; HT, hypertension; SD, standard deviation; NCA, normal coronary flow (control group); CAD, coronary artery disease; TIMI, thrombolysis in myocardial infarction; LAD, left anterior descending artery; LCx, left circumflex artery; RCA, right coronary artery; IQR, interquartile range