. Author manuscript; available in PMC: 2017 Sep 1.

Published in final edited form as: J Urol. 2016 Mar 17;196(3):892–901. doi: 10.1016/j.juro.2016.03.077

Table 1.

Effect of prostatitis on urinary bladder cystometric assessment.

	saline	zym 7d	zym-14d	zym-21d	zym-28d
Mean peak pressure (mmHg) during micturition	20.0 ± 2.1	28.4 ± 2.2^*	29.9 ± 3.9^*	28.5 ± 2.2^*	24.8 ± 2.4
Micturition pressure threshold (mmHg)	26.6 ± 2.3	14.4 ± 3.4^*	16.7 ± 4.1^*	18.2 ± 4.2^*	17.7 ± 4.7^*
Intercontraction interval (sec)	156.2 ± 1.9	92.5 ± 1.4^*	80.0 ± 2.74^*	78.0 ± 1.9^*	82.6 ± 2.4^*
Time to first micturition (sec)	283.8 ± 31.1	215.6 ± 33.5^*	238.2 ± 28.1	221.6 ± 26.5^*	228.2 ± 26.1
# Micturition events/20 min	8.6 ± 1.6	13.6 ± 1.9^*	16.2 ± 2.4^*	14.0 ± 2.1^*	13.7 ± 2.4
Baseline pressure (prior to infusion)	1.4 ± 0.4	2.5 ± 0.8	1.9 ± 0.5	2.6 ± 0.4	1.9 ± 0.1

Data are presented as mean ± SEM from control (saline)- and zymosan (zym)- treated mice 7 – 28 days after intra-prostate injection of zym. n=8 mice/treatment group.

p≤0.05 vs. control, two-way ANOVA with Bonferroni post-hoc test.