Table 2.
Altered ambulatory BP profile and cardiovascular events in patients with CKD
| Study design | Patients (n) | ABP profiles/outcomes | References |
|---|---|---|---|
| Cross-sectional | African Americans with CKD (n = 617) | Proteinuria and LVH more common in patients with elevated nighttime BP and masked hypertension | Pogue et al.42 |
| Cross-sectional | CKD pts (n = 540) | Reverse dipper BP pattern closely related to worse renal function and severe CV damage | Wang et al.45 |
| Cross-sectional | CKD pts (n = 1219) | BP load and ABP levels correlated with LVMI, eGFR, and proteinuria; nighttime SBP load correlated with TOD in pts with nondiabetic CKD | Wang et al.46 |
| Longitudinal (follow-up >4 yr) | Veterans with CKD (n = 274) | Rate of growth of LVMI was rapid in first 2 years and plateaued subsequently; clinic BP and 24-hour ABP were associated with LVMI and its growth over time | Agarwal47 |
| Cross-sectional | CKD pts (n = 1492) | Masked hypertension was independently associated with low eGFR, higher proteinuria, and higher LVMI and pulse wave | Drawz et al.48 |
ABP, ambulatory blood pressure; BP, blood pressure; CKD, chronic kidney disease; CV, cardiovascular; eGFR, estimated glomerular filtration rate; LV, left ventricular; LVH, left ventricular hypertrophy; LVMI, left ventricular mass index; pts, patients; SBP, systolic blood pressure; TOD, target organ damage.