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TGF-β signaling regulates G1/S checkpoint in CAFs. (A) The analysis of cell cycle regulation pathway. Proteins of which expression changed more than 2 folds and involved in cell cycle regulation were presented (B) The possible pathway regulating G1/S checkpoint. (C) Verification of the possible pathway regulating G1/S checkpoint. (D) The expression of TGF-β2 in colon cancer tissue. FSP1 is a marker of CAF.
