Table 3.
List of the 119 SiRNA targeting the selected 56 genes
| No. | Symbol | Viable cell density (%) |
per cell luciferase yield (%) |
Gene_ID | siRNA sequence | Biological process |
|---|---|---|---|---|---|---|
| 1 | APOBEC3H | 66.938 | 227.583 | 164668 | AGAGGCUACUUUGAAAACAtt | RNA processing/Spliceosome |
| 2 | APOBEC3H | 88.955 | 171.805 | 164668 | CAAGUCACCUGUUACCUCAtt | RNA processing/Spliceosome |
| 3 | HNRNPC | 73.809 | 227.741 | 3183 | ACACUCUUGUGGUCAAGAAtt | RNA processing/Spliceosome |
| 4 | HNRNPC | 96.599 | 184.201 | 3183 | GAUGAAGAAUGAUAAGUCAtt | RNA processing/Spliceosome |
| 5 | HNRNPC | 97.392 | 163.496 | 3183 | CAACGGGACUAUUAUGAUAtt | RNA processing/Spliceosome |
| 6 | HNRPDL | 75.879 | 227.884 | 9987 | CCCGGAUACUUCUGAAGAAtt | RNA processing/Spliceosome |
| 7 | HNRPDL | 108.214 | 140.868 | 9987 | GAACGAGUACAGCAAUAUAtt | RNA processing/Spliceosome |
| 8 | INTS1 | 83.129 | 238.606 | 26173 | GUUCAUCCAUAAGUACAUUtt | RNA processing/Spliceosome |
| 9 | INTS1 | 96.256 | 153.438 | 26173 | AGAUCUUUGUCAAGGUGUAtt | RNA processing/Spliceosome |
| 10 | INTS2 | 88.908 | 185.522 | 57508 | GACAUUGGAUCAUACUAAAtt | RNA processing/Spliceosome |
| 11 | INTS2 | 103.888 | 156.977 | 57508 | GGCGAAUGCUCCUGACUAAtt | RNA processing/Spliceosome |
| 12 | PRPF19 | 94.579 | 170.349 | 27339 | GCGCAAGCUUAAGAACUUUtt | RNA processing/Spliceosome |
| 13 | PRPF19 | 97.007 | 170.088 | 27339 | GCUCAUCGACAUCAAAGUUtt | RNA processing/Spliceosome |
| 14 | RBM22 | 63.879 | 256.443 | 55696 | CCAUAUAUCCGAAUGACCAtt | RNA processing/Spliceosome |
| 15 | RBM22 | 71.395 | 212.652 | 55696 | CGGAAUCAAUGAUCCUGUAtt | RNA processing/Spliceosome |
| 16 | SART1 | 51.696 | 275.068 | 9092 | GCAUCGAGGAGACUAACAAtt | RNA processing/Spliceosome |
| 17 | SART1 | 77.169 | 257.929 | 9092 | CAAUGAUUCUUACCCUCAAtt | RNA processing/Spliceosome |
| 18 | SF3B3 | 49.133 | 300.611 | 23450 | CAACCUUAUUAUCAUUGAAtt | RNA processing/Spliceosome |
| 19 | SF3B3 | 62.659 | 233.649 | 23450 | GUUUCAUCUGGGUUCGCUAtt | RNA processing/Spliceosome |
| 20 | SF3B4 | 35.915 | 409.361 | 10262 | GCAUCAGCUCACAACAAAAtt | RNA processing/Spliceosome |
| 21 | SF3B4 | 55.962 | 266.627 | 10262 | GUCCUAUCACCGUAUCUUAtt | RNA processing/Spliceosome |
| 22 | SNRPB | 54.559 | 388.072 | 6628 | AGAUACUGGUAUUGCUCGAtt | RNA processing/Spliceosome |
| 23 | SNRPB | 53.645 | 370.824 | 6628 | UGGUCUCAAUGACAGUAGAtt | RNA processing/Spliceosome |
| 24 | SNRPB | 66.394 | 238.463 | 6628 | GGCUGUACAUAGUCCUUUUtt | RNA processing/Spliceosome |
| 25 | SNRPD2 | 58.901 | 247.842 | 6633 | UGUGGACUGAGGUACCCAAtt | RNA processing/Spliceosome |
| 26 | SNRPD2 | 82.950 | 171.198 | 6633 | CUGCCGCAACAAUAAGAAAtt | RNA processing/Spliceosome |
| 27 | SNRPE | 54.945 | 311.516 | 6635 | GGAUCAUGCUAAAAGGAGAtt | RNA processing/Spliceosome |
| 28 | SNRPE | 64.385 | 226.659 | 6635 | CAUUGGUUUUGAUGAGUAUtt | RNA processing/Spliceosome |
| 29 | SNRPF | 54.854 | 283.281 | 6636 | AGGGCUAUCUGGUAUCUGUtt | RNA processing/Spliceosome |
| 30 | SNRPF | 79.386 | 188.094 | 6636 | GGUGUAAUAAUGUCCUUUAtt | RNA processing/Spliceosome |
| 31 | U2AF1 | 65.083 | 292.710 | 7307 | GAAUAACCGUUGGUUUAAUtt | RNA processing/Spliceosome |
| 32 | U2AF1 | 63.672 | 240.287 | 7307 | GGAACACUAUGAUGAGUUUtt | RNA processing/Spliceosome |
| 33 | U2AF1 | 82.333 | 187.362 | 7307 | GGUGCUCUCGGUUGCACAAtt | RNA processing/Spliceosome |
| 34 | U2AF2 | 54.133 | 311.348 | 11338 | CCAACUACCUGAACGAUGAtt | RNA processing/Spliceosome |
| 35 | U2AF2 | 55.405 | 277.511 | 11338 | CAGCAAACCUUUGACCAGAtt | RNA processing/Spliceosome |
| 36 | CNOT1 | 81.492 | 244.722 | 23019 | GCUAUUUCCAGCGAAUAUAtt | Transcription |
| 37 | CNOT1 | 96.002 | 173.284 | 23019 | GGAGGAAUCUCGAAUGCGAtt | Transcription |
| 38 | KAT5 | 70.586 | 284.565 | 10524 | GGAGAAAGAAUCAACGGAAtt | Transcription |
| 39 | KAT5 | 71.473 | 216.209 | 10524 | GGACGGAAGCGAAAAUCGAtt | Transcription |
| 40 | L3MBTL4 | 63.577 | 250.367 | 91133 | GAACUUCAAUGGAAAACAUtt | Transcription |
| 41 | L3MBTL4 | 77.107 | 210.336 | 91133 | GAUCGUUUGAGAGAACAAAtt | Transcription |
| 42 | MZF1 | 66.872 | 302.994 | 7593 | CAGGUAGUGUAAGCCCUCAtt | Transcription |
| 43 | MZF1 | 49.189 | 299.886 | 7593 | AGGUUACAGAGGACUCAGAtt | Transcription |
| 44 | NKX3-2 | 88.616 | 212.905 | 579 | GAACCGUCGCUACAAGACAtt | Transcription |
| 45 | NKX3-2 | 96.869 | 162.999 | 579 | CCCUCCUACUAUUACCCGUtt | Transcription |
| 46 | POU5F1 | 83.011 | 194.043 | 5460 | GGAGAUAUGCAAAGCAGAAtt | Transcription |
| 47 | POU5F1 | 85.820 | 180.401 | 5460 | GUCCGAGUGUGGUUCUGUAtt | Transcription |
| 48 | RDBP | 97.298 | 183.386 | 7936 | AGAGGACCCAGAUUGUCUAtt | Transcription |
| 49 | RDBP | 111.487 | 145.707 | 7936 | AAGUCAACAUAGCCCGAAAtt | Transcription |
| 50 | TBX1 | 75.599 | 193.846 | 6899 | GCAAAGAUAGCGAGAAAUAtt | Transcription |
| 51 | TBX1 | 91.538 | 161.634 | 6899 | GGAUCACGCAGCUCAAGAUtt | Transcription |
| 52 | ZBTB41 | 85.750 | 176.019 | 360023 | CCAGUUCGACCUGAACAAAtt | Transcription |
| 53 | ZBTB41 | 83.351 | 171.308 | 360023 | GACCUAUACUCAUUCUGCAtt | Transcription |
| 54 | ZNF358 | 61.490 | 256.085 | 140467 | GUUUCGACCUCGAUCCAGAtt | Transcription |
| 55 | ZNF358 | 85.866 | 167.413 | 140467 | CAGCCUCACCAAGCACAAAtt | Transcription |
| 56 | ABCB8 | 57.472 | 294.800 | 11194 | CGACCAUCAUGGAAAACAUtt | Metabolic process |
| 57 | ABCB8 | 103.662 | 146.993 | 11194 | CGCUUUAACUGGAAGCUCUtt | Metabolic process |
| 58 | ACSF2 | 59.084 | 288.857 | 80221 | GAAACUGCAUGAGAAGACAtt | Metabolic process |
| 59 | ACSF2 | 80.013 | 234.608 | 80221 | CGAUGUUCGUGGACAUUCUtt | Metabolic process |
| 60 | ALDH3A2 | 87.831 | 171.072 | 224 | CACUUUCCUGGGUAUUGUAtt | Metabolic process |
| 61 | ALDH3A2 | 115.513 | 141.760 | 224 | CAACAGUACUUACCGAUGUtt | Metabolic process |
| 62 | OAZ1 | 94.839 | 169.972 | 4946 | GCCUUGCUCCGAACCUUCAtt | Metabolic process |
| 63 | OAZ1 | 101.904 | 141.842 | 4946 | GAUUAUCCUUGUACUUUGAtt | Metabolic process |
| 64 | PPP2R1A | 60.645 | 254.007 | 5518 | GAACAGCUGGGAACCUUCAtt | Metabolic process |
| 65 | PPP2R1A | 104.020 | 161.613 | 5518 | CUUCGACAGUACUUCCGGAtt | Metabolic process |
| 66 | PPP2R1A | 96.357 | 157.243 | 5518 | GGAGUUCUUUGAUGAGAAAtt | Metabolic process |
| 67 | 4-Sep | 68.989 | 220.902 | 5414 | GGACCAAGCCCUAAAGGAAtt | Metabolic process |
| 68 | 4-Sep | 110.815 | 140.658 | 5414 | GCAGUGGACAUAGAAGAGAtt | Metabolic process |
| 69 | DENND5B | 76.131 | 235.013 | 160518 | CGAUAUGCUUUUCUACGUUtt | Cation transport |
| 70 | DENND5B | 83.636 | 176.821 | 160518 | CCAGCGAUACAACUCCUAUtt | Cation transport |
| 71 | KCNJ10 | 83.512 | 259.478 | 3766 | GCAGGCACAUGGUUCCUCUtt | Cation transport |
| 72 | KCNJ10 | 105.029 | 161.785 | 3766 | AGGUCAAUGUGACUUUCCAtt | Cation transport |
| 73 | KCTD15 | 76.798 | 186.195 | 79047 | CCAAGUCCAAUGCACCUGUtt | Cation transport |
| 74 | KCTD15 | 88.009 | 174.946 | 79047 | CCUGGACAGUUUGAAGCAAtt | Cation transport |
| 75 | SLC12A8 | 78.156 | 185.175 | 84561 | GCUUCCUCUUGGACCUCAAtt | Cation transport |
| 76 | SLC12A8 | 80.173 | 184.608 | 84561 | GCGGAAAAGGUAUCCCUCAtt | Cation transport |
| 77 | CASP8AP2 | 67.320 | 284.062 | 9994 | CCAACAAGGAAGACGAAAAtt | Apoptotic process |
| 78 | CASP8AP2 | 79.253 | 272.683 | 9994 | CCCUGUUCAUUAUAAGUCUtt | Apoptotic process |
| 79 | CASP8AP2 | 89.677 | 157.868 | 9994 | GGAUAUUGGAGGCUAGUCAtt | Apoptotic process |
| 80 | CDCA7 | 82.689 | 209.398 | 83879 | GACUAUUGAUACCAAAACAtt | Apoptotic process |
| 81 | CDCA7 | 90.976 | 189.252 | 83879 | GCAAUGCUUGCAAAACUCAtt | Apoptotic process |
| 82 | CCT2 | 85.046 | 189.850 | 10576 | CAUUGGUGUUGACAAUCCAtt | Protein folding |
| 83 | CCT2 | 79.093 | 186.786 | 10576 | GUUGCAAACUUAUCGAGGAtt | Protein folding |
| 84 | CCT2 | 91.558 | 160.246 | 10576 | CUCUUAUGGUAACCAAUGAtt | Protein folding |
| 85 | CCT7 | 76.280 | 200.322 | 10574 | AAAUGCAACCCAAAAAGUAtt | Protein folding |
| 86 | CCT7 | 90.987 | 160.687 | 10574 | GUACCUGCGGGAUUACUCAtt | Protein folding |
| 87 | C22orf26 | 93.181 | 185.763 | 55267 | CCACCCUACUAUGUACUGUtt | Miscellaneous |
| 88 | C22orf26 | 94.537 | 155.385 | 55267 | GCUAAGUCUUUUCCACAGUtt | Miscellaneous |
| 89 | C3orf19 | 91.714 | 202.960 | 51244 | CAGUUACUUUCAAAACUCUtt | Miscellaneous |
| 90 | C3orf19 | 92.429 | 156.418 | 51244 | CAACAGAUCAGAGAACAAAtt | Miscellaneous |
| 91 | CHAF1A | 82.390 | 228.483 | 10036 | GCCUGAAUCUUGUCCCAAAtt | Miscellaneous |
| 92 | CHAF1A | 66.511 | 215.853 | 10036 | GAAGAAGACUCUGUACUCAtt | Miscellaneous |
| 93 | CHAF1A | 104.553 | 179.207 | 10036 | CGAAACUUGUCAACGGGAAtt | Miscellaneous |
| 94 | EEF1B2 | 75.570 | 200.070 | 1933 | AGAAAGCUUUGGGCAAAUAtt | Miscellaneous |
| 95 | EEF1B2 | 85.471 | 183.071 | 1933 | GGAAGAACGUCUUGCACAAtt | Miscellaneous |
| 96 | EEFSEC | 101.897 | 162.677 | 60678 | GAACAAAAUAGACCUCUUAtt | Miscellaneous |
| 97 | EEFSEC | 95.368 | 152.850 | 60678 | CUGUGGAAAAGAUACCGUAtt | Miscellaneous |
| 98 | FAM102A | 66.121 | 214.156 | 399665 | GCCCACUAUUCUCAGCUCAtt | Miscellaneous |
| 99 | FAM102A | 105.514 | 143.889 | 399665 | GCAUCUGUCCGAUCGCUCUtt | Miscellaneous |
| 100 | FRZB | 74.811 | 205.132 | 2487 | GGGACACUGUCAACCUCUAtt | Miscellaneous |
| 101 | FRZB | 89.583 | 163.431 | 2487 | CAUCAAGCCCUGUAAGUCUtt | Miscellaneous |
| 102 | ICA1L | 67.947 | 258.104 | 130026 | UGAAGAUAAUCGAGAAAUAtt | Miscellaneous |
| 103 | ICA1L | 100.201 | 153.426 | 130026 | ACAGGUCUUUAUCAAAGCAtt | Miscellaneous |
| 104 | MARK2 | 95.471 | 162.372 | 2011 | GACUCAGAGUAACAACGCAtt | Miscellaneous |
| 105 | MARK2 | 112.248 | 137.554 | 2011 | GCCUAGGAGUUAUCCUCUAtt | Miscellaneous |
| 106 | MFRP | 88.359 | 164.639 | 83552 | CUAACUACCCAGACCCUUAtt | Miscellaneous |
| 107 | MFRP | 105.583 | 154.286 | 83552 | GCAACAGAAUCGAGCAAGAtt | Miscellaneous |
| 108 | MGRN1 | 63.690 | 273.535 | 23295 | CCCUGAAGGUUACCUCUUUtt | Miscellaneous |
| 109 | MGRN1 | 113.437 | 140.103 | 23295 | GGAUGACGAGCUGAACUUUtt | Miscellaneous |
| 110 | OCRL | 123.199 | 150.843 | 4952 | GAUUACUUCUUGACUAUCAtt | Miscellaneous |
| 111 | OCRL | 109.377 | 136.174 | 4952 | CUCCCGCAGUUGAACAUCAtt | Miscellaneous |
| 112 | OR10P1 | 61.943 | 281.113 | 121130 | CUCUGAUUGUCACCUCUUAtt | Miscellaneous |
| 113 | OR10P1 | 91.526 | 179.268 | 121130 | GCUCCUCUGUUACCACAGAtt | Miscellaneous |
| 114 | PRR15 | 102.629 | 146.756 | 222171 | CGCUCACCAACAGCAGAAAtt | Miscellaneous |
| 115 | PRR15 | 110.986 | 133.601 | 222171 | CUUUUAAUGUUAAACUACAtt | Miscellaneous |
| 116 | RAB31 | 84.418 | 228.634 | 11031 | GAACUUCACAAGUUCCUCAtt | Miscellaneous |
| 117 | RAB31 | 89.607 | 180.764 | 11031 | CAAUGGAACAAUCAAAGUUtt | Miscellaneous |
| 118 | TACC2 | 82.634 | 188.258 | 10579 | GGAUUACAGAAACUCCUAUtt | Miscellaneous |
| 119 | TACC2 | 108.211 | 141.104 | 10579 | GAGCAGAGAUCAUAACCAAtt | Miscellaneous |