Table 1.
Subject characteristics
| Baseline Subject Characteristics | Lean | Obese | Obese T2D |
|---|---|---|---|
| Age, yr | 28 ± 1.5 | 55 ± 1.3* | 55 ± 1.7* |
| BMI, kg/m2 | 25.3 ± 1.1 | 34.8 ± 1.4* | 36.5 ± 1.3* |
| Body fat, % | 25.3 ± 2.1 | 38.9 ± 1.8* | 41.3 ± 2.2* |
| GDR, mg·kg LBM−1·min−1 | 12.9 ± 1.2 | 6.6 ± 1.6* | |
| HOMA IR | 1.9 ± 0.4 | 3.1 ± 0.6 | 10.1 ± 2.6*† |
| Glucose, mg/dl | 85 ± 2.5 | 94 ± 2.6 | 135 ± 5.8*† |
| Insulin, µIU/ml | 8.3 ± 1.8 | 13.2 ± 2.5 | 30.3 ± 6.6 |
| Triglycerides, mg/dl | 72 ± 5.6 | 149 ± 27.0* | 135 ± 16.2* |
| Total cholesterol, mg/dl | 167 ± 12.7 | 215 ± 11.1* | 147 ± 10.4† |
Values are mean ± SE. T2D; type 2 diabetes; BMI, body mass index; GDR, glucose disposal rate; LBM, lean body mass; HOMA-IR, homeostatic model assessment of insulin resistance.
*
P < 0.05 from Lean.
†
P < 0.05 from obese.