Table 1.

Plasma sodium and potassium levels in wild-type and Sgk1−/− mice under different treatment conditions

Treatment	Genotype	Plasma Na+, meq/l	Plasma K+, meq/l	Animals
Control	WT	156 ± 2	3.66 ± 0.28	4
	KO	157 ± 1	5.96 ± 0.34†	4
High-K diet	WT	156 ± 3	3.80 ± 0.29	10
	KO	149 ± 2*	5.46 ± 0.36†	7
Aldosterone	WT	142 ± 3	4.01 ± 0.32	4
	KO	146 ± 3	5.06 ± 0.83	4
Control‡	WT	166 ± 1	2.80 ± 0.18	4
	KO	165 ± 1	3.69 ± 0.28*	4
Amiloride‡	WT	148 ± 3	4.26 ± 0.38	3
	KO	151 ± 2	5.84 ± 0.11*	3

^‡Blood collected from the vena cava.

WT, wild type; KO, Sgk1 knockout. Statistical significance vs. WT:

^*P < 0.05,

^†P < 0.01.