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Pharmacokinetics of ELP and KTP-ELP in rodents
| ELP | KTP-ELP | |
|---|---|---|
| Central compartment volume of distribution (Vc), ml | 16.4 | 7.3 |
| Plasma clearance (Cl), ml/min | 0.43 | 0.04 |
| Area under curve (AUC), μg·min−1·ml−1 | 68,907.6 | 350,657.1 |
| Distribution half-life (t1/2,dist), min | 3.63 | 39.12 |
| Terminal half-life (t1/2,term), min | 52.6 | 234.83 |
