Table 3.
Pharmacokinetics of ELP and KTP-ELP in swine
ELP | KTP-ELP | |
---|---|---|
Central compartment volume of distribution (Vc), ml | 1,316.9 | 1,214.5 |
Plasma clearance (Cl), ml/min | 24.3 | 15.3 |
Area under curve (AUC), μg·min−1·ml−1 | 5,962.3 | 9,472.7 |
Distribution half-life (t1/2,dist), min | 3.8 | 6.0 |
Terminal half-life (t1/2,term), min | 90.3 | 118.6 |