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. 2016 Oct 26;312(1):F54–F64. doi: 10.1152/ajprenal.00143.2016

Table 3.

Pharmacokinetics of ELP and KTP-ELP in swine

ELP KTP-ELP
Central compartment volume of distribution (Vc), ml 1,316.9 1,214.5
Plasma clearance (Cl), ml/min 24.3 15.3
Area under curve (AUC), μg·min−1·ml−1 5,962.3 9,472.7
Distribution half-life (t1/2,dist), min 3.8 6.0
Terminal half-life (t1/2,term), min 90.3 118.6