Table 1.

Characterization of fast- and slow-type fibers in diaphragm and hindlimb muscles of WT and obscurin KO mice

	Dia WT	Dia KO	EDL WT	EDL KO	Sol WT	Sol KO
Fast	84.5	83.5	95.5	87.5	39	37.5
Slow	15.5	16.5	4.5	12.5*	61	62.5

Values are calculated from n = 4 independent experiments. Units are %. No significant differences in the count of fast vs. slow fiber type were observed in diaphragm (Dia) and soleus (Sol) muscles between wild-type (WT) and obscurin knockout (KO) mice. A shift toward the slow phenotype was detected in the extensor digitorum longus (EDL) of obscurin KO mice (

^*P < 0.05).