Table 1.

Cell types in the large intestine

Cells Involved in Tonic Inhibition	Cells Involved in CMMC Contractions
Longitudinal smooth muscle	Longitudinal smooth muscle
Circular smooth muscle	Circular smooth muscle
Inhibitory motor neurons	Intrinsic primary afferent neurons
Serotonergic interneurons	Ascending interneurons
Glia	Excitatory motor neurons
ICC-IM	Inhibitory motor neurons
PDGFRα+	Serotonergic interneurons
ICC-MY*	Glia
ICC-SMP†	PDGFRα+
Submucosal neurons	ICC-IM
	ICC-MY*
	ICC-SMP†
	Submucosal neurons
	Enterochrommaffin cells

CMCC, colonic migrating motor complex; ICC-IM, intramuscular interstitial cells of Cajal; ICC-MY, myenteric pacemaker interstitial cells of Cajal; ICC-SMP, submucosal pacemaker interstitial cells of Cajal; PDGFRα+, platelet-derived growth factor-receptor α-positive cells.

^*ICC-MY cells generate myenteric potential oscillations.

^†ICC-SMP cells generate electrical slow waves.