Fig. 2.

Chronic hyperglycemia results in depressed LV hemodynamics. A: LV pressure (P) and first derivative of LV pressure (dP/dt) measurements for one naïve male FVB mouse (Ctrl; left) and one STZ-treated male FVB mouse ~3 mo after induction of diabetes (right). B: hemodynamic parameters under isoflurane anesthesia for naïve male FVB mice (Ctrl, n = 13–15) and STZ-treated male FVB mice at 2 to 3 and 4–6 mo after diabetes (STZ, n = 15) are shown as means ± SE *P < 0.05 vs. Ctrl for the same time point.