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. 2016 Oct 27;49(1):27–36. doi: 10.1152/physiolgenomics.00072.2016

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Fig. 2. — Comparison of serotonin (5-HT)-mediated vasoconstriction in MCAs isolated from FHH and FHH.1^BN rats. MCAs were mounted on glass micropipettes in a myograph, and the intraluminal pressure was maintained at 80 mmHg. After 1 h of equilibration at 37°C, 5-HT was applied to the vessel. A: representative diameter traces of 5-HT-mediated dose-dependent vasoconstriction in MCAs. B: percent constriction of MCAs plotted against log10 concentrations of 5-HT. The continuous lines are the best fit to the Hill equation. C: bar graph depicting the percent constriction in response to 0.1 and 1 μM 5-HT. *P < 0.05 between FHH and FHH.1^BN rats. Error bars ± SE. Numbers in parentheses indicate the number of vessels studied.