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. 2016 Oct 27;49(1):27–36. doi: 10.1152/physiolgenomics.00072.2016

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Fig. 4. — Comparison of 5-HT-mediated inhibition of large conductance potassium channel (BK) currents in VSMCs isolated from MCA of FHH and FHH.1^BN rats. Current-voltage curves of whole-cell BK currents in the presence and absence (control) of 4-aminopyridine (4-AP) combined with and without 3 μM 5-HT. A: K⁺ channel current densities plotted over membrane potential (4 cells). B: summary graph of current density at +80 mV (4 cells). *Significant difference in the corresponding values between FHH and FHH.1^BN rats; !significant difference in the corresponding values before and after 5-HT in FHH.1^BN rats. Error bars ± SE. Numbers in parentheses indicate the number of VSMCs studied.