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. 2016 Oct 27;49(1):27–36. doi: 10.1152/physiolgenomics.00072.2016

Fig. 7.

Fig. 7.

Comparison of 5-HT-mediated change in cytosolic calcium ([Ca2+]i) in VSMCs isolated from MCA of FHH and FHH.1BN rats. VSMCs were isolated from MCAs and plated on 25 mm glass coverslip in a 1 ml perfusion chamber. We loaded 5 μM fluo 4-AM into the cells and measured [Ca2+]i. A: traces. B: summary graph of change in fluorescence during peak and plateau phases in response to 1 μM 5-HT. *Significant difference in the corresponding values in FHH and FHH.1BN rats. Error bars ± SE. Numbers in parentheses indicate the number of VSMCs studied.