Table 1.
Live endothelialized surface | Anti-FXa activity (U/mg) | Anti-thrombin activity (U/mg) | TriS (%) |
---|---|---|---|
Native aorta | 154 ± 12 | 38 ± 7 | 8 |
HUVECs | 800 ± 21 | 200 ± 9 | 48 |
HUVECs/Native aorta (ratio) | 5.2 | 5.3 | 6 |
FXa and thrombin assays were used for anti-FXa and anti-thrombin activity assessment, and TriS percentage was measured by established LC-MS. The results are mean ± SD of five independent assays using five different rats and HUVECs cultures (n=5).